What is NeuroQuant?
NeuroQuant is an FDA approved tool that aids clinicians in the workup and diagnosis of patients presenting with symptoms relating to memory and cognition. It provides an objective measure of brain volume, specifically the volume of brain structures commonly damaged by Alzheimer’s Disease. It then compares these volumes to a national database of patients of the same age, sex and skull size who have healthy brains.
With this information, NeuroQuant provides you and your healthcare team a very valuable tool in the workup for patients who have mild, moderate or severe cognitive impairment. NeuroQuant can increase the confidence that the symptoms are due to neuronal loss, rather than other possibilities including medication side effects, anxiety/depression, sleep apnea, or nutritional deficiency, among others. Research has shown a correlation between the size of the hippocampus and the onset of Alzheimer’s disease, with hippocampal atrophy beginning as early as ten years before symptoms present. Patients who have a smaller hippocampus are four times more likely to progress to Alzheimer’s disease than patients whose hippocampus is a normal size. The hippocampus in a healthy patient shrinks about 1 percent per year compared to about 5 percent per year in a person with Alzheimer’s disease.
Why Choose NeuroQuant?
NeuroQuant can monitor changes in brain atrophy over time to determine if and how quickly a disease is progressing. The study also may help to measure the effect of treatment and identify patients most likely to benefit from aggressive intervention.
Although normal-sized brain structures can’t rule out dementia, high-functioning patients concerned about mild but increasing memory loss may be reassured by NeuroQuant results in the normal range.
Features and Benefits:
- Used by medical professionals to aid in quantifying atrophy and assessing neurodegenerative diseases
- First FDA cleared, CE marked, and Health Canada, Australia, and Korea licensed software for volumetric MRI processing
- Provides volumetric measurements of brain structures and compares the volumes to a normative database adjusted for age, gender and intracranial volume
- A powerful tool to help physicians evaluate patients from ages 3 to 100
- Supports the physician’s clinical impression with quantitative numbers
- Provides clinicians with objective data to help in the assessment of patients’ prognoses and clinical courses
- Helps physicians identify and assess neurodegeneration in its earliest stages to aid in treatment and lifestyle planning for patients
Before Arriving for Your Exam
We encourage patients to pre-register for their appointment and complete the MRI Screening Questionnaire and the MRI and Pregnancy form (if applicable). This will help speed up your registration process.
If you are claustrophobic (fearful of small, enclosed areas) or experience pain when lying on your back for more than 30 minutes, your referring physician may prescribe a relaxant or pain medication to help you through the exam. Please let the IMI Team know of any concerns upon scheduling your appointment, so we can make certain you have what you need to complete your exam successfully.
We don’t anticipate a long wait time, however, we want to make any waiting time as pleasant as possible. Consider bringing your favorite magazine, book or music with headphones to help you pass the time.
- Unless you are told otherwise, take your regular medications as usual.
- Please leave your jewelry and valuables at home.
- You will be asked to wear scrubs during the exam.
Please tell the technologist, radiology nurse and/or imaging physician of any allergies you may have and if you are pregnant or are nursing.
You will be asked to fill out a questionnaire which will determine if an MRI is safe for you. People with various implants (usually metallic), body piercings or with metal in their bodies (including some tattoos) may have difficulty with an MRI – which utilizes a strong magnetic field. The imaging physician needs to be informed of any of these potential problems.
During the Exam
An MRI machine consists of a large cylinder-shaped tube with a movable table that slides into the center of the machine. For this exam, you will be asked to lie down on the scanning table, head-first with arms at your side. Coils (special devices to improve image quality) may be placed around your head. The scanning table will slide your whole body into the magnet.
During the scan you will not feel anything but will hear intermittent humming, thumping, clicking and knocking sounds. Earplugs will be provided to help mask the noise and to allow you to listen to music. In most cases, the imaging physician requests a contrast agent (dye) to improve the quality of the images. The contrast agent is injected into a vein in the arm, which may cause a cool sensation. As your images are taken, you must hold very still, in some cases, you will be asked to hold your breath. The technologist is always able to see and hear you during the exam.
After Your Exam
There are no restrictions placed upon you. You may eat or drive as normal. Your images will be examined by a radiologist and their report will be sent to your healthcare provider. Your healthcare provider will review the results with you.